The safety and pharmacokinetics of carisoprodol in patients with renal impairment weren’t evaluated. Since carisoprodol is excreted with the kidney, caution must be exercised if carisoprodol is administered to patients with impaired renal function. Carisoprodol is dialyzable by hemodialysis and peritoneal dialysis.
Patients should be advised that treatment with Carisoprodol ought to be limited by acute use (up to 2-3 weeks) for your relief of acute, musculoskeletal discomfort. In the post-marketing experience with Carisoprodol, cases of dependence, withdrawal, and abuse are actually reported with prolonged use. If the musculoskeletal symptoms still persist, patients should contact their doctor for even more evaluation.
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Carisoprodol is really a centrally acting skeletal muscle relaxant that will not directly relax skeletal muscles.A metabolite of carisoprodol, meprobamate, has anxiolytic and sedative properties. The degree to which these properties of meprobamate contribute to the security and efficacy of carisoprodol is unknown.